Study findings that a family history of acne and various lifestyle factors were associated with adult acne in women was among recent developments in acne reported on Healio.com/Dermatology. Other recent developments included research finding a combination of a superficial chemical peel, subcision and fractional CO2 laser resurfacing after tumescent anesthesia is a safe and effective treatment for rolling acne scars.
Improved Understanding of Inflammation in Acne Pathophysiology: Leading to New Developments in Treatment
New technologies have shown the presence of inflammatory pathways throughout all stages of acne lesion formation. Our understanding of the pathophysiology of AV is evolving as new technologies have shown the presence of inflammatory pathways throughout all stages of acne lesion formation. As our understanding of the pathophysiology of AV increases, researchers can focus on targeting specific points in cascades of inflammation as they develop new therapies to treat AV. Advances in immunohistochemistry and other research techniques have brought forth new information on AV pathophysiology.
The FDA’s approval of Allergan plc’s Aczone Gel, 7.5% as a once-daily topical treatment for patients with acne was a recent development reported on Healio.com/Dermatology. Other recent developments included research presented at the American Academy of Dermatology Annual Meeting on acne treatment and the public’s misconceptions of patients with acne.
The topical nitric oxide-releasing gel, SB204, is safe and effective, and further research on the novel treatment for acne vulgaris is warranted, according to research presented at the American Academy of Dermatology Annual Meeting.
Novan has announced in a press release that dosing has begun in its phase 3 trial of SB204 Gel, its topical nitric oxide product candidate, for treating acne vulgaris. Two identical phase 3 trials are being conducted in parallel, and Novan expects to report the phase 3 results in the first half of 2017, according to the release.